PATIENTS | Locally-advanced Head And Neck Cancer

Locally-advanced Head And Neck Cancer

Head and neck cancer that has spread to local tissue and lymph nodes

Clinical Trial Results
  • Based on phase II study, if Theracim was added to the combination of radiotherapy and chemotherapy in patients with locally-advanced head and neck cancer, the possibility to stay alive at 5-year was 31% higher compared with radiotherapy and chemotherapy alone.
  • The combination of Theracim, chemotherapy and radiotherapy was also showed to be well tolerated by patient9.

TheraCIM Gemcitabine


*Your doctor may recommend treatment with Theracim based on the stage of your cancer, or your overall health. Please consult with your doctor for more information.

What is head and neck cancer?

Head and neck cancer is a type of cancer that starts in the tissues and organs of the head and neck. They include cancers of the larynx (voice box), throat, lips, mouth, nose, and salivary glands. Most head and neck cancers begin in squamous cells, which are cells that line moist surfaces such as those inside the head and neck (for example, the mouth, nose, and throat).

This type of head and neck cancer is called squamous cell carcinoma head and neck cancer (SCCHN). Locally advanced unresectable SCCHN is a stage of SCCHN which has spread from the site of the original tumor only to surrounding tissue or lymph nodes and cannot be removed completely through surgery.

How many people have head and neck cancer?

If you have head and neck cancer, you are not alone!

Head and neck cancer is a common cancer, with a number of new case in the world in 2012 is 600,000 cases. Head and neck cancer is more common in men and was reported to have higher lifetime risk for men than for women.

What are the risk factors for getting head and neck cancer?

It is important to know that having 1 or more risk factors does not mean that you will certainly have head and neck cancer and some people may get this type of cancer even if they don’t have any risk factors. The risk factors that is associated with head and neck cancer, including:


Tobacco use
Cigarette smoking is a strong risk factor for head and neck cancer independent of alcohol drinking. Smoking frequency, duration, and cumulative consumption is associated with increased risk for getting head and neck cancer


Heavy alcohol use
In the patients that never smokes, the association between alcohol consumption and the risk of head and neck cancer is only apparent at high doses of alcohol.


Infection with human papillomavirus (HPV)
HPV is a type of virus that is commonly transmitted sexually. HPV infection is high-risk for with one type of head and neck cancer that occur in oropharynx, which is in the middle part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx8.